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Fare Guide

Estimated lowest fares found within 7 days

The cheapest airline(s) flying from Des Moines to Chicago is United Airlines.

Travel Period: December 2024 - November 2025

The cheapest month(s) to fly from Des Moines to Chicago is December.

Dec 2024
Jan 2025
Feb 2025
Mar 2025
Apr 2025
May 2025
Jun 2025
Jul 2025
Aug 2025
Sep 2025
Oct 2025
Nov 2025

The cheapest day(s) of the week to fly from Des Moines to Chicago is Friday.

Sun Sunday
Mon Monday
Tue Tuesday
Wed Wednesday
Thu Thursday
Fri Friday
Sat Saturday

Flight Schedules

Last Updated: Sat, 2 Nov, 2024

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
- Latest
Duration
- Shortest
- Longest
Stopover
All
Airline Filter by Airline
View All Airline
Availability
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18:47 DSM

20:20 ORD

1Hrs, 33m Direct
DSMDes Moines Airport 18:47 - ORD 20:20 1h 33m Direct
DSMDes Moines Airport 18:47
ORDChicago O'Hare International Airport 20:20
1h 33m
Direct
United Airlines (UA 5599)Crj Canadair Regional
United Airlines (UA 5599)
- -
- -
- -
- -
- F
- -
- -
Crj Canadair Regional

18:54 DSM

20:22 ORD

1Hrs, 28m Direct
DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
DSMDes Moines Airport 18:54
ORDChicago O'Hare International Airport 20:22
1h 28m
Direct
United Airlines (UA 1807)Airbus
United Airlines (UA 1807)
- -
- T
- W
- -
- -
- -
- -
Airbus

18:54 DSM

20:25 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 18:54 - ORD 20:25 1h 31m Direct
DSMDes Moines Airport 18:54
ORDChicago O'Hare International Airport 20:25
1h 31m
Direct
United Airlines (UA 5599)Embraer 175
United Airlines (UA 5599)
- -
- -
- -
- -
- -
- S
- -
Embraer 175

18:54 DSM

20:22 ORD

1Hrs, 28m Direct
DSMDes Moines Airport 18:54 - ORD 20:22 1h 28m Direct
DSMDes Moines Airport 18:54
ORDChicago O'Hare International Airport 20:22
1h 28m
Direct
United Airlines (UA 1807)Airbus
United Airlines (UA 1807)
- M
- -
- -
- T
- -
- -
- S
Airbus

05:20 DSM

06:52 ORD

1Hrs, 32m Direct
DSMDes Moines Airport 05:20 - ORD 06:52 1h 32m Direct
DSMDes Moines Airport 05:20
ORDChicago O'Hare International Airport 06:52
1h 32m
Direct
American Airlines (AA 6389)Crj 700 Canadair Regional
American Airlines (AA 6389)
- M
- T
- W
- T
- F
- S
- S
Crj 700 Canadair Regional

08:00 DSM

09:27 ORD

1Hrs, 27m Direct
DSMDes Moines Airport 08:00 - ORD 09:27 1h 27m Direct
DSMDes Moines Airport 08:00
ORDChicago O'Hare International Airport 09:27
1h 27m
Direct
United Airlines (UA 1363)Boeing 737 800
United Airlines (UA 1363)
- M
- T
- W
- T
- F
- S
- S
Boeing 737 800

11:25 DSM

12:56 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
DSMDes Moines Airport 11:25
ORDChicago O'Hare International Airport 12:56
1h 31m
Direct
United Airlines (UA 3597)Embraer 170
United Airlines (UA 3597)
- -
- -
- -
- -
- -
- S
- S
Embraer 170

11:25 DSM

12:53 ORD

1Hrs, 28m Direct
DSMDes Moines Airport 11:25 - ORD 12:53 1h 28m Direct
DSMDes Moines Airport 11:25
ORDChicago O'Hare International Airport 12:53
1h 28m
Direct
United Airlines (UA 2306)Airbus
United Airlines (UA 2306)
- M
- T
- W
- T
- -
- -
- -
Airbus

11:25 DSM

12:56 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 11:25 - ORD 12:56 1h 31m Direct
DSMDes Moines Airport 11:25
ORDChicago O'Hare International Airport 12:56
1h 31m
Direct
United Airlines (UA 4725)Embraer 175
United Airlines (UA 4725)
- -
- -
- -
- -
- F
- -
- -
Embraer 175

11:41 DSM

13:15 ORD

1Hrs, 34m Direct
DSMDes Moines Airport 11:41 - ORD 13:15 1h 34m Direct
DSMDes Moines Airport 11:41
ORDChicago O'Hare International Airport 13:15
1h 34m
Direct
American Airlines (AA 6084)Crj Canadair Regional
American Airlines (AA 6084)
- -
- -
- -
- T
- F
- -
- S
Crj Canadair Regional

11:44 DSM

13:15 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 11:44 - ORD 13:15 1h 31m Direct
DSMDes Moines Airport 11:44
ORDChicago O'Hare International Airport 13:15
1h 31m
Direct
American Airlines (AA 4703)Embraer Emb 175
American Airlines (AA 4703)
- -
- -
- W
- -
- -
- -
- -
Embraer Emb 175

11:50 DSM

13:21 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 11:50 - ORD 13:21 1h 31m Direct
DSMDes Moines Airport 11:50
ORDChicago O'Hare International Airport 13:21
1h 31m
Direct
American Airlines (AA 4703)Embraer Emb 175
American Airlines (AA 4703)
- M
- -
- -
- -
- -
- -
- -
Embraer Emb 175

15:20 DSM

16:48 ORD

1Hrs, 28m Direct
DSMDes Moines Airport 15:20 - ORD 16:48 1h 28m Direct
DSMDes Moines Airport 15:20
ORDChicago O'Hare International Airport 16:48
1h 28m
Direct
United Airlines (UA 1568)Airbus
United Airlines (UA 1568)
- M
- T
- W
- T
- F
- S
- S
Airbus

16:00 DSM

17:34 ORD

1Hrs, 34m Direct
DSMDes Moines Airport 16:00 - ORD 17:34 1h 34m Direct
DSMDes Moines Airport 16:00
ORDChicago O'Hare International Airport 17:34
1h 34m
Direct
American Airlines (AA 6047)Crj Canadair Regional
American Airlines (AA 6047)
- -
- -
- -
- T
- F
- -
- S
Crj Canadair Regional

17:09 DSM

18:43 ORD

1Hrs, 34m Direct
DSMDes Moines Airport 17:09 - ORD 18:43 1h 34m Direct
DSMDes Moines Airport 17:09
ORDChicago O'Hare International Airport 18:43
1h 34m
Direct
American Airlines (AA 6047)Crj Canadair Regional
American Airlines (AA 6047)
- -
- -
- -
- -
- -
- S
- -
Crj Canadair Regional

17:09 DSM

18:40 ORD

1Hrs, 31m Direct
DSMDes Moines Airport 17:09 - ORD 18:40 1h 31m Direct
DSMDes Moines Airport 17:09
ORDChicago O'Hare International Airport 18:40
1h 31m
Direct
American Airlines (AA 4703)Embraer Emb 175
American Airlines (AA 4703)
- -
- T
- -
- -
- -
- -
- -
Embraer Emb 175

17:16 DSM

18:50 ORD

1Hrs, 34m Direct
DSMDes Moines Airport 17:16 - ORD 18:50 1h 34m Direct
DSMDes Moines Airport 17:16
ORDChicago O'Hare International Airport 18:50
1h 34m
Direct
American Airlines (AA 6047)Crj Canadair Regional
American Airlines (AA 6047)
- M
- -
- W
- -
- -
- -
- -
Crj Canadair Regional

18:25 DSM

23:05 MDW

4Hrs, 40m 1 Stop (STL)
DSMDes Moines Airport 18:25 - MDW 23:05 4h 40m 1 Stop (STL) Saint Louis
DSMDes Moines Airport 18:25

STLSt Louis Lambert Intl Airport 21:55
STLSt Louis Lambert Intl Airport 19:30

MDWChicago Midway Airport 23:05
4h 40m (2h 25m)
1 Stop STL · Saint Louis 2h 25m
Southwest Airlines (WN 2925)Boeing 737 700

Southwest Airlines (WN 652)Boeing 737 800
Southwest Airlines (WN 2925)
- M
- -
- -
- T
- F
- -
- S

05:30 DSM

09:25 MDW

3Hrs, 55m 1 Stop (STL)
DSMDes Moines Airport 05:30 - MDW 09:25 3h 55m 1 Stop (STL) Saint Louis
DSMDes Moines Airport 05:30

STLSt Louis Lambert Intl Airport 08:15
STLSt Louis Lambert Intl Airport 06:50

MDWChicago Midway Airport 09:25
3h 55m (1h 25m)
1 Stop STL · Saint Louis 1h 25m
Southwest Airlines (WN 372)Boeing 737 700

Southwest Airlines (WN 498)Boeing 737 700
Southwest Airlines (WN 372)
- -
- -
- -
- -
- -
- S
- -

16:10 DSM

20:05 MDW

3Hrs, 55m 1 Stop (STL)
DSMDes Moines Airport 16:10 - MDW 20:05 3h 55m 1 Stop (STL) Saint Louis
DSMDes Moines Airport 16:10

STLSt Louis Lambert Intl Airport 18:55
STLSt Louis Lambert Intl Airport 17:15

MDWChicago Midway Airport 20:05
3h 55m (1h 40m)
1 Stop STL · Saint Louis 1h 40m
Southwest Airlines (WN 2925)Boeing 737 800

Southwest Airlines (WN 1253)Boeing 737 700
Southwest Airlines (WN 2925)
- -
- T
- W
- -
- -
- -
- -

Sorry, there are no schedules matching your filters. Try removing one. reset

What’s the fastest flight time from Des Moines to Chicago?

The fastest flight time for direct flights from Des Moines to Chicago is 1 hour 27 minutes. Check latest flight schedules & prices on Wego.

How far is Chicago from Des Moines?

The flight distance between Des Moines and Chicago is 497km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 05:20. The last flight of the day departs at 18:25. See the full list of flight times on Wego.

How many airlines offer direct flights from Des Moines to Chicago?

There are 2 airlines that offer direct flights from Des Moines to Chicago. Find out the list of airlines on Wego.

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